Researchers Find Help against Diabetic Complications from Common Mushroom
The English common name for the tree mushroom Ganoderma applanatum is 'Artist Conk,' due to the fact that the light pores on its underbelly stain brown when etched, thus supplying a nature-made canvas for artists.
According to American tree expert David Arora - author of mushroom identification guide Mushrooms Demystified - Artist Conk is "the most common conk in our area [USA]," along with Red-belted Conk (Fomitopsis pinicola). [400] Artist Conks can grow huge and live for 50 years.
"The only regions where [Artist Conk] seems to be absent are those where there aren't any trees!" says Arora. [400] It can grow on most hardwood trees plus some conifers species, like the northwestern Douglas Fir.
Our ancestors would burn Artist Conk because it produced not only a pleasant odor but an insect repelling smoke as well. [25]
In 2008, a study by Jeong et al. stated that an isolated compound from Artist Conk "significantly inhibited the growth of solid tumor [Sarcoma-180] and increased the natural killer (NK) cell activity." [401] NK cells, or Natural Killer cells, are white blood cells that form a vital part in the human immune system's cancer fighting arsenal. At least four additional studies have also reported positive findings in regards to the anti-tumor properties of Ganoderma applanatum. [402, 403, 404, 405]
An area more unique to the research on this particular mushroom species is its influence on blood sugar levels and preventing diabetic complications. A 2007 study concluded that an isolate from Artist Conk lowered blood sugar levels by an average of 22.0% and blood lipids (cholesterol and triglycerides) by 20.3% [406] The lowering effect on blood glucose levels by an alcohol extract of Ganoderma applanatum had been previously reported by Jung et al. in 2005. [407]
However, the main purpose of the 2005 study by Jung was to assess Artist Conk's effect on inhibiting aldose reductase, an enzyme that's considered responsible for the organ complications seen in diabetics. It is commonly believed that inhibiting aldose reductase in diabetics could have a major effect on decreasing side-effects of diabetes. Jung reports that "these results suggested that G. applanatum [Artist Conk] might possess constituents with anti-diabetic and inhibitory effects on diabetic complications." [407] Two other studies have also found Artist Conk exhibiting significant aldose reductase inhibiting properties. [408, 409]
Looking at other research on Artist Conk, a 2005 study reported a polysaccharide extract of Artist Conk as strengthening the gastric mucosa barrier, useful in cases gastric ulcers. [410] Other papers have reported Artist Conk extracts as anti-viral, [414] anti-bacterial, [411, 412, 413] anti-parasitic and diuretic, [415] antioxidant, [416] and immune boosting. [25]
In addition, Paul Stamets also lists respiratory conditions and inflammation as areas where research has shown Artist Conk extract to be beneficial, in his book Mycelium Running. [134]
Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Never use any herb (or mushroom) except as advised by a licensed medical practitioner. - 17273
According to American tree expert David Arora - author of mushroom identification guide Mushrooms Demystified - Artist Conk is "the most common conk in our area [USA]," along with Red-belted Conk (Fomitopsis pinicola). [400] Artist Conks can grow huge and live for 50 years.
"The only regions where [Artist Conk] seems to be absent are those where there aren't any trees!" says Arora. [400] It can grow on most hardwood trees plus some conifers species, like the northwestern Douglas Fir.
Our ancestors would burn Artist Conk because it produced not only a pleasant odor but an insect repelling smoke as well. [25]
In 2008, a study by Jeong et al. stated that an isolated compound from Artist Conk "significantly inhibited the growth of solid tumor [Sarcoma-180] and increased the natural killer (NK) cell activity." [401] NK cells, or Natural Killer cells, are white blood cells that form a vital part in the human immune system's cancer fighting arsenal. At least four additional studies have also reported positive findings in regards to the anti-tumor properties of Ganoderma applanatum. [402, 403, 404, 405]
An area more unique to the research on this particular mushroom species is its influence on blood sugar levels and preventing diabetic complications. A 2007 study concluded that an isolate from Artist Conk lowered blood sugar levels by an average of 22.0% and blood lipids (cholesterol and triglycerides) by 20.3% [406] The lowering effect on blood glucose levels by an alcohol extract of Ganoderma applanatum had been previously reported by Jung et al. in 2005. [407]
However, the main purpose of the 2005 study by Jung was to assess Artist Conk's effect on inhibiting aldose reductase, an enzyme that's considered responsible for the organ complications seen in diabetics. It is commonly believed that inhibiting aldose reductase in diabetics could have a major effect on decreasing side-effects of diabetes. Jung reports that "these results suggested that G. applanatum [Artist Conk] might possess constituents with anti-diabetic and inhibitory effects on diabetic complications." [407] Two other studies have also found Artist Conk exhibiting significant aldose reductase inhibiting properties. [408, 409]
Looking at other research on Artist Conk, a 2005 study reported a polysaccharide extract of Artist Conk as strengthening the gastric mucosa barrier, useful in cases gastric ulcers. [410] Other papers have reported Artist Conk extracts as anti-viral, [414] anti-bacterial, [411, 412, 413] anti-parasitic and diuretic, [415] antioxidant, [416] and immune boosting. [25]
In addition, Paul Stamets also lists respiratory conditions and inflammation as areas where research has shown Artist Conk extract to be beneficial, in his book Mycelium Running. [134]
Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Never use any herb (or mushroom) except as advised by a licensed medical practitioner. - 17273
About the Author:
Dr. Rafael has worked with natural health since finishing Chiropractic College in the mid-90's. He currently focuses on medicinal mushrooms, working with the extracts of Paul Stamets, including the synergistic MycoSoft Gold Formula including Artist Conk. For research references to this article, please visit the Ganoderma applanatum medicinal research page.
posted by X - Men at
12:47 PM
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