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Tuesday, July 7, 2009

Reishi Hot Water Extract vs. Alcohol Extract

By Dr. Markho Rafael

For two millennia, medicinal mushrooms have been mainstream in Asia. Now, America is taking notice and interest is rapidly "mushrooming." With the sprouting of this new industry follows issues of ethical quality claims between competing brands.

All species of medicinal mushrooms appear haunted by this issue. Particularly so, it seems, is red reishi (Ganoderma lucidum), the oldest medicinal mushroom in Traditional Chinese Medicine. Please note, however, that the information in this article applies generally to all medicinal mushroom species.

The first and perhaps obvious caution is to stay away from cheap mass-produced brands of medicinal mushrooms that may only contain dried and pulverized mushrooms, in which case the medicinal compounds are still inaccessible behind the mushrooms' cell walls.

But even among the truly effective therapeutic brands, which are plentiful, there are important differences. Each seems to claim superiority over other brands, not surprisingly, because why else would anyone buy them? This article aims to clarify the confusion of conflicting and sometimes misleading information that is out there.

There are primarily three ways to extract the medicinal compounds from red reishi. Each method pulls out different compounds, all of which have been proven by scientific research to be therapeutically important.

1. Water Extraction, Hot (polysaccharides and more)

2. Alcohol Extraction (triterpenoids, etc.)

3. Fermented (arabinoxylanes, etc.)

The water soluble compounds, primarily polysaccharides, are powerful anti-tumor agents, immune enhancers and strong antioxidants. [1]

Through alcohol extraction, we get triterpenoids, a large group of lipids with many sub-groups. Research shows triterpenoids help regulate clotting, blood pressure and cholesterol. More importantly, they are the anti-inflammatory compounds that are the reason why reishi often gets recommended for arthritis, asthma and allergies. [1]

And then there are the new and unique medicinal compounds that get created when reishi is fermented. These "secondary metabolites" have their own therapeutic properties, different from the first two groups, including anti-tumor, immune support and blood-sugar balance. [2]

This article is intended to give general guidelines to help you choose an effective reishi product, not to recommend any particular brand. But there are at least two reishi companies on the market which both state only hot water extract is useful while alcohol extracts are of no value.

Naturally, the reason they say so is because they want to sell their own brand. However, those statements are scientifically untrue. Hot water and alcohol extractions both contain critical compounds.

When looking for the best reishi extract, find one that uses at least the first two extraction methods in combination: Hot Water and Alcohol Extraction. Even better may be a brand that includes all three methods listed.

An additional point to keep in mind is the form the reishi comes in. Reishi that dissolves completely in a water-based liquid such as coffee probably only contains reishi from hot water extraction. As a substitute for regular coffee, this would be a superb health-choice. However, it will not contain the water-insoluble triterpenoids so valued for their anti-inflammatory properties.

Surprisingly, though, alcohol tinctures may include both hot water extract and alcohol extract. You will know if the alcohol tincture contains polysaccharides because when the alcohol and hot water extracts are blended, the polysaccharides fall out of solution and the tincture becomes cloudy. (Just shake it before you take it.) A cloudy medicinal mushroom tincture is an indication of high polysaccharide content. Capsules and tablets may be either hot water extract or alcohol extract or both.

[1] Boh B, Berovic M, Zhang J, Zhi-Bin L, 2007. "Ganoderma lucidum and its pharmaceutically active compounds." Biotechnology Annu Rev 13:265-301.

[2] Tang YJ, Zhang W, Zhong JJ, 2009. "Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum." Bioresource Technol. Mar;100(5):1852-9. - 17273

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